No More Anxiety. No More Insomnia.
A drug-free, FDA-cleared treatment you control
No More Anxiety. No More Insomnia.
A drug-free, FDA-cleared treatment you control
Alpha-Stim neuromodulation devices are proven to be safe and effective for treating anxiety and insomnia. No medications required. Alpha-Stim can be used alone or alongside other anxiety and insomnia treatment options.
The Benefits of Using Alpha-Stim
Alpha-Stim has been clinically evaluated as a safe, medication-free alternative to insomnia, anti-anxiety medications, and pain meds.
- In a clinical trial of Alpha-Stim patients, after 6 weeks, users experienced 42.8% improvement.5
It’s also been shown that Alpha-Stim saves you money in the long run, while prescription drugs add up to high costs over time.
Plus, no lasting side effects or risk of addiction.
How Well Does Alpha-Stim Work?
Backed by research spanning decades, Alpha-Stim is clinically proven to treat anxiety and insomnia. Below are highlighted clinical outcomes from Alpha-Stim technologies using cranial electrotherapy stimulation (CES).
*FDA-cleared for treating anxiety, insomnia, and pain in the United States, with approval for depression outside of the United States.
Overall Decrease in Anxiety
In clinical trials, patients reported an average of 61% less anxiety immediately after using the CES therapy. After 5 weeks, that average was 94%.2
Better Than Anxiety Medication
In clinical studies, patients using Alpha-Stim reported greater relief from anxiety than patients taking drugs, all without side effects.1
20 Minutes to Anxiety Relief
In a study of preoperative anxiety, Alpha-Stim recipients reported significantly less anxiety after one 20-minute treatment.4
Improve Sleep Quality
In one study, the number of subjects rating their quality of sleep as poor dropped from 60% to 5% after using Alpha-Stim CES therapy.6
More Time Asleep
After only 5 Alpha-Stim insomnia treatments, military service members with insomnia reported an increase of 43 minutes of sleep.7
Preferred Over Medication
One survey showed patients feel better with Alpha-Stim insomnia treatment than with common sleep drugs.8
Which Alpha-Stim Device is Right for You?
Compact and lightweight, Alpha-Stim fits in the palm of your hand. Its earclips are as small as earbuds, providing rapid, discreet relief at home, in a clinic, or at work.
- Alpha-Stim M: Ideal if you’re struggling with pain in addition to anxiety and/or insomnia. Alpha-Stim M is unique for its ability to treat pain locally at the source of the pain with AS-Trodes™ or Smart Probes.
- Alpha-Stim AID: If improving your mental health and sleep is your focus, this is an ideal choice. Alpha-Stim AID is unique in its ability to treat anxiety and insomnia in one device.
See if Alpha-Stim is right for you
Alpha-Stim empowers you to take control of your life again. Whether exploring Alpha-Stim for anxiety or insomnia, or both, see if this FDA-cleared device is a good fit today.
✓ Concierge Telehealth Option
✓ Fast Prescription Review for Non-Healthcare Professionals
✓ 30-Day Money-Back Guarantee
✓ Flexible Payment Options
✓ Dedicated Support
✓ HSA/FSA Eligible
✓ Special discounts for First Responders, Active Military, Veterans & Healthcare Professionals
How to Purchase an Alpha-Stim
How to Buy Alpha-Stim
Alpha-Stim is trusted by individuals and healthcare professionals nationwide for managing anxiety and insomnia, as well as supporting longevity in overall health and wellness routines.
You can buy an Alpha-Stim device in any of the following ways:
✔ HSA funds
✔ FSA funds
✔ Credit or debit card
✔ Monthly payment plan* (available in most locations)
Special discounts:
Exclusive pricing and discounts available for:
✔ First Responders
✔ Veterans & Active Military
✔ Healthcare Professionals
Do I need a prescription?
Yes. A prescription is required, so you can book a quick telehealth appointment online or have your healthcare practitioner fill out the Statement of Medical Necessity Form, then you just submit it when you purchase your device online.
*FDA-cleared for treating anxiety, insomnia, and pain in the United States, with approval for depression outside of the United States.
Backed By Research. Used Worldwide.
Alpha-Stim is trusted by individuals and healthcare professionals around the world for managing anxiety and insomnia, as well as supporting longevity in overall health and wellness routines.
Trusted and Proven:
✔ FDA-cleared
✔ 100+ clinical studies, surveys, and more
✔ Decades of research
✔ Drug-free and non-invasive
✔ Non-invasive
Used By:
✔ Healthcare professionals
✔ Veterans & Active Military
✔ Elite performers and athletes
✔ First responders
✔ Mental health specialists
Get More Information About Alpha-Stim
Want to get more information about Alpha-Stim? Want to get your questions answered and learn about available discounts? Just fill out the form below, and we’ll be in touch!
Commonly Asked Questions
Commonly Asked Questions about Alpha-Stim
We’ve gotten a few questions over the years about how Alpha-Stim neuromodulation devices work. See below for some of our most common questions and answers.
Does Alpha-Stim actually work?
Alpha-Stim has been shown to be effective in the treatment of anxiety, insomnia, depression, and pain, supported by decades of clinical research, including peer-reviewed studies and clinical trials. On average, Alpha-Stim helps more than 90% of patients.*
Some individuals notice benefits quickly, while for others it may take several weeks of consistent use.
While the majority of users experience positive results, Alpha-Stim may not be effective for everyone. For this reason, we offer a 60-day return policy to ensure peace of mind as you explore whether Alpha-Stim is right for you.
*Real-world data was obtained through a patient survey evaluating the outcomes associated with the use of Alpha-Stim in adherence to prescribed protocols. This data complements clinical testing and provides additional insights into the use of the device. For comprehensive evidence and detailed information regarding clinical studies on Alpha-Stim, please visit: www.alpha-stim.com/research.
What is Cranial Electrotherapy Stimulation?
Great question! Cranial Electrotherapy Stimulation, or CES, is a non-invasive treatment that uses low-intensity electrical currents to stimulate the brain. CES aims to normalize brainwave activity and potentially alleviate symptoms associated with anxiety, depression, insomnia, and pain.
Alpha-Stim CES specifically is a form of non-invasive brain stimulation that applies a patented, low-amplitude waveform to the brain via earclip electrodes. Why do we use CES? Psychiatric disorders, such as anxiety and insomnia, are associated with alterations in electrical activity in large-scale brain networks.
And research suggests Alpha-Stim CES modulates large-scale brain network activity patterns in two synergistic ways, which you can learn more about here.
How quickly do people notice results with Alpha-Stim?
Alpha-Stim effectively treats your anxiety and insomnia.
Many people using Alpha-Stim send us messages saying how well it works and report feeling calmer and more relaxed, experiencing less anxiety, and sleeping better. Some people find immediate anxiety relief with Alpha-Stim, while some need a few weeks to notice a significant change.
With Alpha-Stim, we routinely hear about how it’s helping people sleep longer, get better quality sleep, works better than common medications like melatonin, and is also helping reduce anxiety.
Some people find immediate relief with Alpha-Stim for insomnia, while some may need a few weeks to notice a significant improvement in sleep quality and duration.
Is Alpha-Stim a VNS device?
No. Alpha-Stim is a CES device.
Due to the similarity in using an electrical current or earclip electrode application, Alpha-Stim can commonly be misidentified as a VNS device or auricular vagus nerve stimulation (aVNS) devices.
And while Alpha-Stim does interact with the vagus nerve, there are key differences in the types of stimulation Alpha-Stim utilizes and the brain regions it targets. You can learn more here.
How long will I need to use Alpha-Stim?
Alpha-Stim effectively treats your anxiety, insomnia, depression, and pain. For some conditions, results are experienced immediately, while for others, a small amount of time and persistence provide the needed relief and results. Learn more about how long to use Alpha-Stim and when to decrease usage here.
Is Alpha-Stim safe for everyday use?
There is no risk of addiction, overuse, or chemical dependency. Treatments generally last between 20 to 60 minutes. The effects of Alpha-Stim are cumulative.
The typical recommended protocol includes:
- Initial Phase: Daily use for about 2 to 3 weeks or until your symptoms are balanced.
- Maintenance Phase: After the initial period, many users find they can scale back to using it every other day or just 2 to 3 times per week.
Is Alpha-Stim the same as other CES devices?
No. Not all CES devices are the same. And this is why researching a device is critical. Below are some things that make Alpha-Stim stand out from other CES devices in the market:
- Alpha-Stim uses a patented waveform, making the stimulation it uses distinct from other CES devices.
- Decades of clinical evidence demonstrate safety and long-term efficacy.
- Alpha-Stim delivers cumulative results that build over time for long-lasting anxiety, insomnia & depression* relief.
- Alpha-Stim stimulates the brain to normalize the pathological signaling in the default mode network that is observed in psychiatric disorders, providing rapid, effective, and lasting symptom relief without the side effects of medication [In simpler terms, Alpha-Stim CES modulates the brain network associated with anxiety, insomnia, and depression to help bring it back to “normal”]
- Alpha-Stim also offers the ability to treat pain. This is another differentiator between other CES devices and Alpha-Stim.
Do I need both Alpha-Stim and a VNS device?
The short answer? No. See why below.
VNS devices are designed specifically to target the vagus nerve, whereas Alpha-Stim works in a broader capacity through cranial electrotherapy stimulation (CES) delivered via the earlobes. This approach interacts with vagal pathways along with other cranial nerve networks, which is part of why Alpha-Stim is FDA-cleared for the treatment of anxiety, insomnia, and pain only, with approval for depression outside of the United States.
To better understand how Alpha-Stim works, Ryan Gober, PhD, the Medical Science Liaison at Electromedical Products International, explains:
“Alpha-Stim uses a low intensity, patented waveform delivered through bilateral earclip electrodes to modulate cortical activity in the temporal lobe of the brain and to stimulate nearby key cranial nerves, including the vagus, trigeminal, and vestibulocochlear nerves that project to deeper subcortical brain structures. Through these two synergistic mechanisms, Alpha-Stim has been shown to modulate activity in the default mode network (DMN), which is widely reported to exhibit altered connectivity in a number of mental health conditions, including anxiety and insomnia.”
Is Alpha-Stim better for anxiety than a VNS device?
Regulatory authorization differs across VNS and non-VNS devices. Alpha-Stim is FDA-cleared (Class II) with defined, labeled indications, whereas other non-invasive products are often marketed in the United States solely as general-wellness devices (GWDs) and are not cleared to treat medical conditions. Alpha-Stim CES is cleared for the treatment of anxiety and insomnia, and Alpha-Stim M’s MET technology is cleared for pain management.
In practical terms, FDA clearance means the device has been reviewed in accordance with applicable regulatory requirements for specific medical indications, and the manufacturer has provided supporting evidence—including performance testing and clinical data—demonstrating that the device meets FDA expectations for safety, performance, and labeling. In contrast, general wellness products are not reviewed or cleared by the FDA for specific medical claims or indications.
Always verify each device’s clearance, labeling, and supporting evidence when choosing a treatment option.
As such, Alpha-Stim offers a unique combination of mechanistic overlap with vagus nerve–targeting devices and the regulatory assurance of FDA clearance for clinical use. (Outside the United States, Alpha-Stim is approved for treating anxiety, insomnia, and pain, as well as depression.)
In conclusion, clinical research suggests Alpha-Stim CES works via a multimodal mechanism involving indirect stimulation of the vagus nerve as well as cortical brain regions that have been linked to anxiety and insomnia.
Moreover, Alpha-Stim is evidence-based, with numerous clinical studies supporting FDA clearance to treat symptoms of anxiety and insomnia as reflected in the device’s labeling. This combined stimulation of cranial nerves and cortical brain regions, along with differences in regulatory authorization, distinguishes Alpha-Stim from devices focused solely on non-invasive VNS/aVNS.
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Sources:
- 1 Barclay TH, Barclay RD. A clinical Trial of cranial electrotherapy stimulation for anxiety and comorbid depression. Journal of Affective Disorders. 2014; 164:171-177. Presented at the American Psychological Association National Conference, Honolulu, July 2013.
- 2 Barclay TH, Barclay RD. A clinical Trial of cranial electrotherapy stimulation for anxiety and comorbid depression. Journal of Affective Disorders. 2014;164:171-177. Presented at the American Psychological Association National Conference, Honolulu, July 2013.
- 3 Holubec, Jerry T. Cumulative response from cranial electrotherapy stimulation (CES) for chronic pain. Practical Pain Management. 2009; 9(9):80-83..
- 4 Lee S-H, Kim W-Y, Lee C-H, et al. Effects of cranial electrotherapy stimulation on preoperative anxiety, pain and endocrine response. Journal of International Medical Research. 2013; 41(6) 1788–1795.
- 5 Platoni K, Oakley R, Haltiwanger SG, Kirsch TB, Marksberry J and Price LR. First responder research shows that electrical brain stimulation helps control anxiety, insomnia, and depression. JJ Psych Behav Sci. 2019; 6(1): 25-31.
- 6 Lichtbroun AS, Raicer MMC, Smith RB. The treatment of fibromyalgia with Cranial Electrotherapy Stimulation. Journal of Clinical Rheumatology. 2001; 7(2):72-78.
- 7 Lande RG, Gragnani C. Efficacy of Cranial Electric Stimulation for the treatment of insomnia: A randomized pilot study. Complementary Therapies in Medicine. 2013; 21(1):8-13.
- 8 Kirsch, D.L., Price, L.R., Nichols, F., Marksberry, J.A., & Platoni, K.T. Military Service Member and Veteran Self-Reports of Efficacy of Cranial Electrotherapy Stimulation for Anxiety, PTSD, Insomnia, and Depression. (2014). The Army Medical Department Journal, 46-54.
- 9 Tan, Gabriel, Rintala, Diana, Jensen, Mark P., Richards, J. Scott, Holmes, Sally Ann, Parachuri, Rama, Lashgari-Saegh, Shamsi and Price, Larry R. Efficacy of cranial electrotherapy stimulation for neuropathic pain following spinal cord injury: a multi-site randomized controlled trial with a secondary 6-month open-label phase. The Journal of Spinal Cord Medicine. 2011; 34(3):285-296.
- 10 Taylor AG, Anderson JG, Riedel SL, et al. Cranial Electrotherapy Stimulation improves symptoms and functional status in individuals with fibromyalgia. Pain Management Nursing. 2013 Dec; 14(4):327-335.
- 10 Kirsch, D.L., Price, L.R., Nichols, F., Marksberry, J.A., & Platoni, K.T. Military Service Member and Veteran Self-Reports of Efficacy of Cranial Electrotherapy Stimulation for Anxiety, PTSD, Insomnia, and Depression. (2014). The Army Medical Department Journal, 46-54.
- 11 Winick, Reid L. Cranial electrotherapy stimulation (CES): a safe and effective low cost means of anxiety control in a dental practice. General Dentistry. 1999; 47(1):50-55.