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Alpha-Stim Clinical Outcomes

Backed by research spanning decades, Alpha-Stim® is clinically proven to treat anxiety, insomnia, depression*, and acute, chronic, and post-traumatic pain. Below are highlighted clinical outcomes from Alpha-Stim technologies using cranial electrotherapy stimulation (CES) and microcurrent electrical therapy (MET).

View full studies, surveys, and clinical evidence here >

*FDA-cleared for treating anxiety, insomnia, and pain in the United States, with approval for depression outside of the United States.

decrease in depression

Decrease in Depression

In clinical trials, Alpha-Stim recipients reported an 82% decrease of ≥ 50% or greater in depression scores after five weeks using the CES therapy.1

overall decrease in anxiety

Overall Decrease in Anxiety

In clinical trials, patients reported an average of 61% less anxiety immediately after using the CES therapy. After 5 weeks, that average was 94%.2

Severe Pain Reduction

In a study of patients with severe pain, Alpha-Stim M significantly reduced pain by an average of 71% after only five treatments.3

decrease in depression

Decrease in Depression

In clinical trials, Alpha-Stim recipients reported an 82% decrease of ≥ 50% or greater in depression scores after five weeks using the CES therapy.1

overall decrease in anxiety

Overall Decrease in Anxiety

In clinical trials, patients reported an average of 61% less anxiety immediately after using the CES therapy. After 5 weeks, that average was 94%.2

Severe Pain Reduction

In a study of patients with severe pain, Alpha-Stim M significantly reduced pain by an average of 71% after only five treatments.3

Better Than Anxiety Medication

In clinical studies, patients using Alpha-Stim reported greater relief from anxiety than patients taking drugs, all without side effects.1

results in one application

20 Minutes to Anxiety Relief

In a study of preoperative anxiety, Alpha-Stim recipients reported significantly less anxiety after one 20-minute treatment.2

Feel Better Faster

In a clinical trial of Alpha-Stim patients, after 6 weeks, users experienced 42.8% improvement.5

Better Than Anxiety Medication

In clinical studies, patients using Alpha-Stim reported greater relief from anxiety than patients taking drugs, all without side effects.1

results in one application

20 Minutes to Anxiety Relief

In a study of preoperative anxiety, Alpha-Stim recipients reported significantly less anxiety after one 20-minute treatment.2

Feel Better Faster

In a clinical trial of Alpha-Stim patients, after 6 weeks, users experienced 42.8% improvement.5

improved sleep quality

Improve Sleep Quality

In one study, the number of subjects rating their quality of sleep as poor dropped from 60% to 5% after using Alpha-Stim CES therapy.6

increased sleep time

More Time Asleep

After only 5 Alpha-Stim insomnia treatments, military service members with insomnia reported an increase of 43 minutes of sleep.7

Preferred Over Medication

One survey showed patients feel better with Alpha-Stim insomnia treatment than with common sleep drugs.8

improved sleep quality

Improve Sleep Quality

In one study, the number of subjects rating their quality of sleep as poor dropped from 60% to 5% after using Alpha-Stim CES therapy.6

increased sleep time

More Time Asleep

After only 5 Alpha-Stim insomnia treatments, military service members with insomnia reported an increase of 43 minutes of sleep.7

Preferred Over Medication

One survey showed patients feel better with Alpha-Stim insomnia treatment than with common sleep drugs.8

Decrease in Post-Traumatic Pain

In a post-traumatic pain study, 56% of patients at 3 months and 85% at 6 months were somewhat or very satisfied with the device for reducing pain levels.9

Better Than Drug-Treatments

When compared to pain relief responses from patients using Vicodin and OxyContin, patients self-reported greater reductions in pain with Alpha-Stim.10

decrease dental anxiety by 61% with Alpha-Stim

Significantly Reduces Dental Anxiety

The effectiveness of Alpha-Stim on dentist-specific anxiety has been studied, and patients reported an average of 61% less anxiety during procedures.11

Decrease in Post-Traumatic Pain

In a post-traumatic pain study, 56% of patients at 3 months and 85% at 6 months were somewhat or very satisfied with the device for reducing pain levels.9

Better Than Drug-Treatments

When compared to pain relief responses from patients using Vicodin and OxyContin, patients self-reported greater reductions in pain with Alpha-Stim.10

decrease dental anxiety by 61% with Alpha-Stim

Significantly Reduces Dental Anxiety

The effectiveness of Alpha-Stim on dentist-specific anxiety has been studied, and patients reported an average of 61% less anxiety during procedures.11

See if Alpha-Stim is right for you

Alpha-Stim empowers you to take control of your life again. Whether exploring Alpha-Stim for yourself or as a healthcare practitioner looking to provide more to patients, see if this FDA-cleared device is a good fit today.

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Sources:

  • 1 Barclay TH, Barclay RD. A clinical Trial of cranial electrotherapy stimulation for anxiety and comorbid depression. Journal of Affective Disorders. 2014; 164:171-177. Presented at the American Psychological Association National Conference, Honolulu, July 2013.
  • 2 Barclay TH, Barclay RD. A clinical Trial of cranial electrotherapy stimulation for anxiety and comorbid depression. Journal of Affective Disorders. 2014;164:171-177. Presented at the American Psychological Association National Conference, Honolulu, July 2013.
  • 3  Holubec, Jerry T. Cumulative response from cranial electrotherapy stimulation (CES) for chronic pain. Practical Pain Management. 2009; 9(9):80-83..
  • 4  Lee S-H, Kim W-Y, Lee C-H, et al. Effects of cranial electrotherapy stimulation on preoperative anxiety, pain and endocrine response. Journal of International Medical Research. 2013; 41(6) 1788–1795.
  • 5 Platoni K, Oakley R, Haltiwanger SG, Kirsch TB, Marksberry J and Price LR. First responder research shows that electrical brain stimulation helps control anxiety, insomnia, and depression. JJ Psych Behav Sci. 2019; 6(1): 25-31.
  • 6 Lichtbroun AS, Raicer MMC, Smith RB. The treatment of fibromyalgia with Cranial Electrotherapy Stimulation. Journal of Clinical Rheumatology. 2001; 7(2):72-78.
  • 7  Lande RG, Gragnani C. Efficacy of Cranial Electric Stimulation for the treatment of insomnia: A randomized pilot study. Complementary Therapies in Medicine. 2013; 21(1):8-13.
  • 8 Kirsch, D.L., Price, L.R., Nichols, F., Marksberry, J.A., & Platoni, K.T. Military Service Member and Veteran Self-Reports of Efficacy of Cranial Electrotherapy Stimulation for Anxiety, PTSD, Insomnia, and Depression. (2014). The Army Medical Department Journal, 46-54.
  • 9  Tan, Gabriel, Rintala, Diana, Jensen, Mark P., Richards, J. Scott, Holmes, Sally Ann, Parachuri, Rama, Lashgari-Saegh, Shamsi and Price, Larry R. Efficacy of cranial electrotherapy stimulation for neuropathic pain following spinal cord injury: a multi-site randomized controlled trial with a secondary 6-month open-label phase. The Journal of Spinal Cord Medicine. 2011; 34(3):285-296.
    • 10 Taylor AG, Anderson JG, Riedel SL, et al. Cranial Electrotherapy Stimulation improves symptoms and functional status in individuals with fibromyalgia. Pain Management Nursing. 2013 Dec; 14(4):327-335.
  • 10 Kirsch, D.L., Price, L.R., Nichols, F., Marksberry, J.A., & Platoni, K.T. Military Service Member and Veteran Self-Reports of Efficacy of Cranial Electrotherapy Stimulation for Anxiety, PTSD, Insomnia, and Depression. (2014). The Army Medical Department Journal, 46-54.
  • 11 Winick, Reid L. Cranial electrotherapy stimulation (CES): a safe and effective low cost means of anxiety control in a dental practice. General Dentistry. 1999; 47(1):50-55.

 

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